Advancing research & scholarship in the stem cell field while staying committed to a deep-rooted Catholic identity.

The Center for Stem Cells and Regenerative Medicine at the University of Notre Dame is an interdisciplinary enterprise, bringing together biologists, biomolecular engineers, lawyers, philosophers, and theologians to advance the research and application of adult stem cells and induced pluripotent stem (iPS) cells in a wide variety of organisms, while also stimulating the ethical and legal discussion associated with stem cells and their use.

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Notre Dame researchers study potential cause of common birth defect

Dovichi

Small ubiquitin-like modifier (SUMO) proteins are small peptides that get added on to other proteins to regulate their activity. While SUMO has many regulatory roles in cells, it is especially important for controlling gene expression during early development. Just a few years ago this connection between SUMO and gene regulation was relatively unknown, but now, Notre Dame researchers are exploring how a disruption to the SUMO protein’s ability to regulate embryo development may be linked to congenital heart defects. 

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